Modeling of antibody-drug conjugate pharmacokinetics [electronic resource] / Dhaval K. Shah.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Periodic reports: Publisher: London : Henry Stewart Talks, 2019Description: 1 online resource (1 streaming video file (49 min.) : color, sound)Subject(s): Antibody-drug conjugates | Antineoplastic agents | Drug development | Antibodies, Monoclonal -- pharmacokinetics | Antineoplastic Agents -- therapeutic use | Computer Simulation | Drug Design | Drug Discovery -- methods | Immunoconjugates -- pharmacokinetics | Immunoconjugates -- pharmacology | Maytansine | Models, Biological | TrastuzumabOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Antibody drug conjugates (ADCs) and their uses -- Different ways to measure ADCs in the cell -- Typical ADC PK in cells -- Modeling the cellular PK of ADCs -- Modeling the tumor PK of ADCs -- 7 steps -- Modeling whole-body PK of ADCs -- Combining PK and PD models -- Kadcyla case study.
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Mode of access: World Wide Web.