The importance of nucleotide size in the chemistry and biology of DNA [electronic resource] / Eric Kool.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Chemical biology : the role of chemistry in our fundamental understanding of biology: Publisher: London : Henry Stewart Talks, 2020Description: 1 online resource (1 streaming video file (41 min.) : color, sound)Subject(s): DNA | Nucleotides | Benzine -- chemistry | Biophysics | DNA Replication | DNA -- chemistry | Hydrogen Bonding | Nucleosides -- chemistry | Nucleotides -- chemistryOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Updated version of a talk first published in 2008.
Contents: Chemical and biophysical properties of size-expanded DNA bases (xDNA) -- Structure of xDNA -- Design of benzo-widened DNA bases (yDNA) -- Non-polar nucleoside isosteres -- Base pair replication without hydrogen bonds -- Base analogues with systematically varied size -- Steric effects in DNA replication in vitro and in vivo.
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Mode of access: World Wide Web.