Kool, Eric,
The importance of nucleotide size in the chemistry and biology of DNA [electronic resource] / Eric Kool. - London : Henry Stewart Talks, 2020. - 1 online resource (1 streaming video file (41 min.) : color, sound). - Chemical biology : the role of chemistry in our fundamental understanding of biology, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Chemical biology : the role of chemistry in our fundamental understanding of biology. .
Animated audio-visual presentation with synchronized narration. Title from title frames. Updated version of a talk first published in 2008.
Contents: Chemical and biophysical properties of size-expanded DNA bases (xDNA) -- Structure of xDNA -- Design of benzo-widened DNA bases (yDNA) -- Non-polar nucleoside isosteres -- Base pair replication without hydrogen bonds -- Base analogues with systematically varied size -- Steric effects in DNA replication in vitro and in vivo.
Access restricted to subscribers.
Mode of access: World Wide Web.
1210 Henry Stewart Talks
DNA.
Nucleotides.
Benzine--chemistry.
Biophysics.
DNA Replication.
DNA--chemistry.
Hydrogen Bonding.
Nucleosides--chemistry.
Nucleotides--chemistry.
The importance of nucleotide size in the chemistry and biology of DNA [electronic resource] / Eric Kool. - London : Henry Stewart Talks, 2020. - 1 online resource (1 streaming video file (41 min.) : color, sound). - Chemical biology : the role of chemistry in our fundamental understanding of biology, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Chemical biology : the role of chemistry in our fundamental understanding of biology. .
Animated audio-visual presentation with synchronized narration. Title from title frames. Updated version of a talk first published in 2008.
Contents: Chemical and biophysical properties of size-expanded DNA bases (xDNA) -- Structure of xDNA -- Design of benzo-widened DNA bases (yDNA) -- Non-polar nucleoside isosteres -- Base pair replication without hydrogen bonds -- Base analogues with systematically varied size -- Steric effects in DNA replication in vitro and in vivo.
Access restricted to subscribers.
Mode of access: World Wide Web.
1210 Henry Stewart Talks
DNA.
Nucleotides.
Benzine--chemistry.
Biophysics.
DNA Replication.
DNA--chemistry.
Hydrogen Bonding.
Nucleosides--chemistry.
Nucleotides--chemistry.