The proteomic revolution [electronic resource] / Larry Gold.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Biomarkers: Publisher: London : Henry Stewart Talks, 2022Description: 1 online resource (1 streaming video file (55 min.) : color, sound)Subject(s): Biochemical markers | Cancer -- Diagnosis | Molecular diagnosis | Proteins -- Analysis | Proteomics -- Methodology | Biomarkers | Cardiovascular Diseases | DNA | Heart Disease Risk Factors | Lung Neoplasms -- diagnosis | Mesothelioma -- diagnosis | Molecular Diagnostic Techniques | Pancreatic Neoplasms -- diagnosis | Pathology, Molecular | Protein Binding | Proteins -- analysis | Proteomics -- methods | Risk Factors | Term BirthOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Updated version of a talk first published in 2012.
Contents: The proteomic revolution -- Proteomics is the best measure of phenotype (biomarkers) -- Slow Off-rate Modified Aptamers (SOMAmers) are breakthrough protein binding reagents -- SOMAmers are multiplexed to perform SOMAscan assay, which measures >1000 proteins in small sample volumes using DNA measurement tools to identify and quantify proteins bound by SOMAmers -- Applications of SOMAscan to date include finding valid protein biomarkers for lung cancer, cardiovascular risk, pre-term birth, pancreatic cancer, mesothelioma, and many other diseases and conditions -- Ability to do comprehensive longitudinal proteomics studies will revolutionize medicine.
Access restricted to subscribers.
Mode of access: World Wide Web.