Gold, Larry.

The proteomic revolution [electronic resource] / Larry Gold. - London : Henry Stewart Talks, 2022. - 1 online resource (1 streaming video file (55 min.) : color, sound). - Biomarkers : the path forward to highly sensitive and specific molecular diagnostics, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Biomarkers. .

Animated audio-visual presentation with synchronized narration. Title from title frames. Updated version of a talk first published in 2012.

Contents: The proteomic revolution -- Proteomics is the best measure of phenotype (biomarkers) -- Slow Off-rate Modified Aptamers (SOMAmers) are breakthrough protein binding reagents -- SOMAmers are multiplexed to perform SOMAscan assay, which measures >1000 proteins in small sample volumes using DNA measurement tools to identify and quantify proteins bound by SOMAmers -- Applications of SOMAscan to date include finding valid protein biomarkers for lung cancer, cardiovascular risk, pre-term birth, pancreatic cancer, mesothelioma, and many other diseases and conditions -- Ability to do comprehensive longitudinal proteomics studies will revolutionize medicine.

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Mode of access: World Wide Web.

3398 Henry Stewart Talks


Biochemical markers.
Cancer--Diagnosis.
Molecular diagnosis.
Proteins--Analysis.
Proteomics--Methodology.
Biomarkers.
Cardiovascular Diseases.
DNA.
Heart Disease Risk Factors.
Lung Neoplasms--diagnosis.
Mesothelioma--diagnosis.
Molecular Diagnostic Techniques.
Pancreatic Neoplasms--diagnosis.
Pathology, Molecular.
Protein Binding.
Proteins--analysis.
Proteomics--methods.
Risk Factors.
Term Birth.
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