Structural basis for Fibroblast Growth Factor (FGF) receptor activation (Record no. 77905)

000 -LEADER
fixed length control field 02484ngm a2200349 a 4500
001 - CONTROL NUMBER
control field HST1231_1_2
003 - CONTROL NUMBER IDENTIFIER
control field UkLoHST
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS
fixed length control field m c
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr|cna|||a||||
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field vz|czazum
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 080121s2007 enk|||||||||||s|||v|eng d
028 50 - PUBLISHER NUMBER
Publisher number 1231
Source Henry Stewart Talks
035 ## - SYSTEM CONTROL NUMBER
System control number (UkLoHST)455
035 ## - SYSTEM CONTROL NUMBER
System control number (UkLU-K)AC000392456
040 ## - CATALOGING SOURCE
Original cataloging agency UkLU-K
Language of cataloging eng
Transcribing agency UkLU-K
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Mohammadi, Moosa.
Relator code spk
245 10 - TITLE STATEMENT
Title Structural basis for Fibroblast Growth Factor (FGF) receptor activation
Medium [electronic resource] :
Remainder of title implications in development and disease /
Statement of responsibility, etc. Moosa Mohammadi.
246 1# - VARYING FORM OF TITLE
Display text Title from publisher's web site:
Title proper/short title Structural biology of FGF signaling in human development and disease
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc. London :
Name of publisher, distributor, etc. Henry Stewart Talks,
Date of publication, distribution, etc. 2007.
300 ## - PHYSICAL DESCRIPTION
Extent 1 online resource (1 streaming video file (41 min.) :
Other physical details color, sound).
490 1# - SERIES STATEMENT
Series statement Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease,
International Standard Serial Number 2056-452X
500 ## - GENERAL NOTE
General note Animated audio-visual presentation with synchronized narration.
500 ## - GENERAL NOTE
General note Title from title frames.
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Contents: FGF family of ligands, and FGF receptor (FGFR) subfamily of receptor tyrosine kinase superfamily -- The roles of FGF signaling in mammalian biology and diseases -- FGFR receptor alternative splicing and its essential role in epithelial-mesenchymal signaling loop, and organogenesis -- Structural mechanism by which FGF and heparan sulfate induce FGFR dimerization and activation on the cell surface -- A working model for FGFR autoinhibition -- Structural mechanisms by which FGF-FGFR binding specificity is achieved -- Structural basis for how alternative splicing regulates ligand-binding specificity of FGFRs -- Structural basis by which ligand-dependent pathogenic mutations in FGFR lead to receptor gain-of-function in human skeletal syndromes -- Structural basis by which alternative splicing regulates patterning ability of FGF8 in the brain.
506 ## - RESTRICTIONS ON ACCESS NOTE
Terms governing access Access restricted to subscribers.
538 ## - SYSTEM DETAILS NOTE
System details note Mode of access: World Wide Web.
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Receptor Protein-Tyrosine Kinases.
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Signal Transduction.
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Henry Stewart talks.
Name of part/section of a work Biomedical & life sciences collection.
-- Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://hstalks.com/bs/455/">https://hstalks.com/bs/455/</a>
856 42 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://hstalks.com/bs/p/38/">https://hstalks.com/bs/p/38/</a>
Materials specified Series

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