Murray, Peter J., Ph. D.
Arginase and nitric oxide [electronic resource] / Peter J. Murray. - London : Henry Stewart Talks, 2011. - 1 online resource (1 streaming video file (39 min.) : color, sound). - Innate immunity : host recognition and response in health and disease, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Innate immunity : host recognition and response in health and disease. .
Animated audio-visual presentation with synchronized narration. Title from title frames. Updated version of a talk first published in 2009.
Contents: Catabolism of arginine to downstream substrates -- Catabolism of arginine in macrophages -- Nitric oxide production -- Control of iNOS at the transcriptional level -- Role of nitric oxide in immunity to intracellular pathogens with a focus on mycobacterial disease -- Structure of arginases -- Transcriptional control of arginase 1 in the liver vs. macrophages -- Arginases can suppress nitric oxide production by substrate depletion -- Pathogens use many mechanisms to regulate nitric oxide -- Arginases and alternatively-activated macrophages (AAMs) -- Schistosome infection as an example of AAM function -- AAMs and arginases -- Arginase inhibition by small molecules -- Outstanding questions.
Access restricted to subscribers.
Mode of access: World Wide Web.
1996 Henry Stewart Talks
Arginase.
Natural immunity.
Nitric oxide.
arginase I, human.
Arginase.
Arginine.
Immunity, Innate.
Macrophages.
Nitric Oxide Synthase Type II.
Nitric Oxide.
NOS2 protein, human.
Arginase and nitric oxide [electronic resource] / Peter J. Murray. - London : Henry Stewart Talks, 2011. - 1 online resource (1 streaming video file (39 min.) : color, sound). - Innate immunity : host recognition and response in health and disease, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Innate immunity : host recognition and response in health and disease. .
Animated audio-visual presentation with synchronized narration. Title from title frames. Updated version of a talk first published in 2009.
Contents: Catabolism of arginine to downstream substrates -- Catabolism of arginine in macrophages -- Nitric oxide production -- Control of iNOS at the transcriptional level -- Role of nitric oxide in immunity to intracellular pathogens with a focus on mycobacterial disease -- Structure of arginases -- Transcriptional control of arginase 1 in the liver vs. macrophages -- Arginases can suppress nitric oxide production by substrate depletion -- Pathogens use many mechanisms to regulate nitric oxide -- Arginases and alternatively-activated macrophages (AAMs) -- Schistosome infection as an example of AAM function -- AAMs and arginases -- Arginase inhibition by small molecules -- Outstanding questions.
Access restricted to subscribers.
Mode of access: World Wide Web.
1996 Henry Stewart Talks
Arginase.
Natural immunity.
Nitric oxide.
arginase I, human.
Arginase.
Arginine.
Immunity, Innate.
Macrophages.
Nitric Oxide Synthase Type II.
Nitric Oxide.
NOS2 protein, human.