Christiani, David C.
Molecular epidemiology of lung cancer [electronic resource] / David C. Christiani. - London : Henry Stewart Talks, 2007. - 1 online resource (1 streaming video file (40 min.) : color, sound). - Gene-environment interactions : role in the modulation of pulmonary and autoimmune disease risks, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Gene-environment interactions : role in the modulation of pulmonary and autoimmune disease risks. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: The influence of host factors on individual susceptibility to tobacco smoke -- The pleiotropic genes that control activation (Phase I) and detoxification (Phase II) of potential carcinogens -- Effects of the metabolism of environmental compounds on the lipophilic properties of a molecule and the introduction of electronegative moieties within the molecule on carcinogenic potential -- Other susceptibility factors related to defects in DNA repair, alterations in tumor suppressor genes and alterations in tumor invasiveness factors -- Polymorphisms in genes and the association of this with lung cancer development -- The role of inherited polymorphisms of genes involved in xenobiotic metabolism, DNA repair and tumor suppression/invasion (alone and in combination) in lung cancer risk, and modification of this risk by environmental factors such as smoking and diet.
Access restricted to subscribers.
Mode of access: World Wide Web.
1176 Henry Stewart Talks
Environmental Exposure.
Genes.
Genetic Predisposition to Disease.
Risk Factors.
Molecular epidemiology of lung cancer [electronic resource] / David C. Christiani. - London : Henry Stewart Talks, 2007. - 1 online resource (1 streaming video file (40 min.) : color, sound). - Gene-environment interactions : role in the modulation of pulmonary and autoimmune disease risks, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Gene-environment interactions : role in the modulation of pulmonary and autoimmune disease risks. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: The influence of host factors on individual susceptibility to tobacco smoke -- The pleiotropic genes that control activation (Phase I) and detoxification (Phase II) of potential carcinogens -- Effects of the metabolism of environmental compounds on the lipophilic properties of a molecule and the introduction of electronegative moieties within the molecule on carcinogenic potential -- Other susceptibility factors related to defects in DNA repair, alterations in tumor suppressor genes and alterations in tumor invasiveness factors -- Polymorphisms in genes and the association of this with lung cancer development -- The role of inherited polymorphisms of genes involved in xenobiotic metabolism, DNA repair and tumor suppression/invasion (alone and in combination) in lung cancer risk, and modification of this risk by environmental factors such as smoking and diet.
Access restricted to subscribers.
Mode of access: World Wide Web.
1176 Henry Stewart Talks
Environmental Exposure.
Genes.
Genetic Predisposition to Disease.
Risk Factors.