Raulet, David H.,

Education of NK cells disarming of autoreactive NK cells [electronic resource] : Title from publisher's web site. Disarming of autoreactive NK cells David H. Raulet. - London : Henry Stewart Talks, 2009. - 1 online resource (1 streaming video file (46 min.) : color, sound). - Natural killer cell biology : natural killer cell-mediated immunity to pathogens and cancer, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Natural killer cell biology : natural killer cell-mediated immunity to pathogens and cancer. .

Animated audio-visual presentation with synchonized narration. Title from title frames.

Contents: NK cell "education" -- NK cells in normal animals attack cells that lack some or all self MHC class I molecules -- NK cells that lack inhibitory receptors for self MHC class I are rendered hyporesponsive and self tolerant -- Hyporesponsiveness of NK cells is induced by target cells lacking MHC I, as in a mixed chimera -- Responsiveness of NK cells varies depending on how many MHC I-specific receptors they express -- NK cell education ensures that NK cells are optimally responsive yet not autoreactive.

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Mode of access: World Wide Web.

2256 Henry Stewart Talks


Cytotoxicity, Immunologic.
Killer Cells, Natural.
Neoplasms.
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