Proudfoot, Amanda E. I.

Chemokines and their receptors their biology and therapeutic relevance / [electronic resource] : Amanda E. I. Proudfoot. - London : Henry Stewart Talks, 2012. - 1 online resource (1 streaming video file (49 min.) : color, sound). - Cells of the innate immune system : roles in health and disease, 2056-452X Cytokines : intercellular mediators regulating host defense, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Cells of the innate immune system. Henry Stewart talks. Biomedical & life sciences collection. Cytokines. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: Chemokines are immune modulators regulating direction of cell migration -- Chemokine receptors are seven transmembrane (7TM) G protein-coupled receptors -- Chemokines need to bind to endothelial expressed proteoglycans for activity in vivo -- Excessive cell recruitment is a hallmark of inflammation -- 7TM receptors are highly druggable targets for the pharmaceutical industry -- Chemokine receptors are an essential co-receptor for HIV infectivity -- Nature uses chemokine binding proteins to iinhibit the chemokine system.

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Mode of access: World Wide Web.

3070 Henry Stewart Talks


Chemokines--Receptors--Effect of drugs on.
Natural immunity.
Chemokines--physiology.
Immunity, Innate.
Receptors, Chemokine--drug effects.
Receptors, Chemokine--physiology.
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