Yamauchi, Yohei,

The role of Neuropilin-1 as a SARS-CoV-2-specific endocytosis potentiator [electronic resource] / an interview with Yohei Yamauchi. - London : Henry Stewart Talks, 2021. - 1 online resource (1 streaming audio file (11 min.)). - Interviews on Covid-19, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Interviews on Covid-19. .

Audio interview. Title from title frames.

Contents: Differences in the structure and biological properties of SARS-CoV-2 Spike proteins compared to those of other coronaviruses (including SARS) -- The distinct profile of the distribution of SARS-CoV-2-infected cells, particularly in lung and epithelial tissue, compared to other coronaviruses -- SARS-CoV-2's Spike protein sequence grants it the unique ability to interact with Neuropilin-1, in addition to ACE2 -- Role of Neuropilin-1, a cell-surface co-receptor, in facilitating mechanisms of SARS-CoV-2 entry into cells -- Current understanding of the influence of Neuropilin-1 on the development of COVID-19 and on disease progression -- The potential of developing SARS-CoV-2-specific antiviral drugs targeting Neuropilin-1.

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Mode of access: World Wide Web.

8214 Henry Stewart Talks


Cell receptors.
Coronaviruses.
COVID-19 (Disease)--Research.
Drug development.
Host-virus relationships.
Angiotensin-Converting Enzyme 2.
Antiviral Agents.
Betacoronavirus--physiology.
Coronavirus infections.
COVID-19--virology.
Endocytosis.
Epithelium.
Lung.
Neuropilin-1.
SARS-CoV-2.
Spike Glycoprotein, Coronavirus--metabolism.
Virus Internalization.
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