The role of Neuropilin-1 as a SARS-CoV-2-specific endocytosis potentiator [electronic resource] / an interview with Yohei Yamauchi.
Material type:
SoundSeries: Henry Stewart talksBiomedical & life sciences collection. Interviews on Covid-19: Publisher: London : Henry Stewart Talks, 2021Description: 1 online resource (1 streaming audio file (11 min.))Subject(s): Cell receptors | Coronaviruses | COVID-19 (Disease) -- Research | Drug development | Host-virus relationships | Angiotensin-Converting Enzyme 2 | Antiviral Agents | Betacoronavirus -- physiology | Coronavirus infections | COVID-19 -- virology | Endocytosis | Epithelium | Lung | Neuropilin-1 | SARS-CoV-2 | Spike Glycoprotein, Coronavirus -- metabolism | Virus InternalizationOnline resources: Click here to access online | Series Audio interview.
Title from title frames.
Contents: Differences in the structure and biological properties of SARS-CoV-2 Spike proteins compared to those of other coronaviruses (including SARS) -- The distinct profile of the distribution of SARS-CoV-2-infected cells, particularly in lung and epithelial tissue, compared to other coronaviruses -- SARS-CoV-2's Spike protein sequence grants it the unique ability to interact with Neuropilin-1, in addition to ACE2 -- Role of Neuropilin-1, a cell-surface co-receptor, in facilitating mechanisms of SARS-CoV-2 entry into cells -- Current understanding of the influence of Neuropilin-1 on the development of COVID-19 and on disease progression -- The potential of developing SARS-CoV-2-specific antiviral drugs targeting Neuropilin-1.
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Mode of access: World Wide Web.