Gibson, Toby,
The role of short linear motifs (SLiMs) in SARS-CoV-2 entry into human cells [electronic resource] / an interview with Toby Gibson. - London : Henry Stewart Talks, 2021. - 1 online resource (1 streaming audio file (12 min.)). - Interviews on Covid-19, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Interviews on Covid-19. .
Audio interview. Title from title frames.
Contents: Rationale and approach to investigating ACE2 and integrin SLiMs -- Update on the mechanism of ACE2- and integrin-mediated viral entry into cells -- SLiMs and their essential role in cellular endocytosis -- Possibility of targeting specific SLiMs as a novel antiviral therapy -- Efficacy of Chloroquine and Chlorpromazine as potential small-molecule therapeutics against viral entry into cells -- The power of interfering with integrin-dependent cellular endocytosis as a proactive defense against coronaviruses.
Access restricted to subscribers.
Mode of access: World Wide Web.
8220 Henry Stewart Talks
Cell receptors.
Coronaviruses.
COVID-19 (Disease)--Research.
COVID-19 (Disease)--Treatment.
Drug development.
Host-virus relationships.
Viruses--Receptors.
Amino Acid Motifs.
Angiotensin-Converting Enzyme 2--chemistry.
Angiotensin-Converting Enzyme 2--physiology.
Antiviral Agents.
Chloroquine.
Chlorpromazine.
COVID-19--therapy.
COVID-19--virology.
Endocytosis.
Host Microbial Interactions.
Integrins--chemistry.
Integrins--physiology.
Models, Biological.
Molecular Targeted Therapy.
SARS-CoV-2--pathogenicity.
SARS-CoV-2--physiology.
Spike Glycoprotein, Coronavirus.
Virus Internalization.
The role of short linear motifs (SLiMs) in SARS-CoV-2 entry into human cells [electronic resource] / an interview with Toby Gibson. - London : Henry Stewart Talks, 2021. - 1 online resource (1 streaming audio file (12 min.)). - Interviews on Covid-19, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Interviews on Covid-19. .
Audio interview. Title from title frames.
Contents: Rationale and approach to investigating ACE2 and integrin SLiMs -- Update on the mechanism of ACE2- and integrin-mediated viral entry into cells -- SLiMs and their essential role in cellular endocytosis -- Possibility of targeting specific SLiMs as a novel antiviral therapy -- Efficacy of Chloroquine and Chlorpromazine as potential small-molecule therapeutics against viral entry into cells -- The power of interfering with integrin-dependent cellular endocytosis as a proactive defense against coronaviruses.
Access restricted to subscribers.
Mode of access: World Wide Web.
8220 Henry Stewart Talks
Cell receptors.
Coronaviruses.
COVID-19 (Disease)--Research.
COVID-19 (Disease)--Treatment.
Drug development.
Host-virus relationships.
Viruses--Receptors.
Amino Acid Motifs.
Angiotensin-Converting Enzyme 2--chemistry.
Angiotensin-Converting Enzyme 2--physiology.
Antiviral Agents.
Chloroquine.
Chlorpromazine.
COVID-19--therapy.
COVID-19--virology.
Endocytosis.
Host Microbial Interactions.
Integrins--chemistry.
Integrins--physiology.
Models, Biological.
Molecular Targeted Therapy.
SARS-CoV-2--pathogenicity.
SARS-CoV-2--physiology.
Spike Glycoprotein, Coronavirus.
Virus Internalization.