Carrington, Mary.

The influence of variation at the killer cell immunoglobulin-like receptor gene complex on human disease [electronic resource] / Mary Carrington. - London : Henry Stewart Talks, 2021. - 1 online resource (1 streaming video file (26 min.) : color, sound). - Natural killer cell biology : natural killer cell-mediated immunity to pathogens and cancer, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Natural killer cell biology : natural killer cell-mediated immunity to pathogens and cancer. .

Animated audio-visual presentation with synchronized narration. Title from title frames. Updated version of a talk first published in 2009.

Contents: Domain structure of human KIRs -- HLA class I and KIR -- Stochastic expression of KIR genes -- HLA ligands for KIRs -- KIR polymorphism -- KIR disease associations: autoimmune, maternal-fetal, cancer and infectious -- NK cell activation probably enhances HCV clearance -- NK cell activation probably protects against persistent HCV infection, reproductive failure and early after HIV infection AIDS progression -- NK cell inhibition probably protects against psoriatic arthritis and cervical neoplasia -- Striking a balance between activating and inhibitory KIR genotypes.

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Mode of access: World Wide Web.

2163 Henry Stewart Talks


Immunogenetics.
Killer cells.
Acquired Immunodeficiency Syndrome--immunology.
Arthritis, Psoriatic--immunology.
Autoimmune Diseases--genetics.
Genetic Variation.
Hepatitis C--immunology.
HIV Infections--immunology.
Infections--genetics.
Infections--immunology.
Killer Cells, Natural--immunology.
Ligands.
Maternal-Fetal Exchange--immunology.
Multigene Family.
Neoplasms--immunology.
Pregnancy--immunology.
Receptors, Immunologic--genetics.
Receptors, Immunologic--metabolism.
Receptors, KIR.
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