Stark, Mike,
Chromosome bi-orientation in yeast [electronic resource] / Mike Stark and Tomo Tanaka. - London : Henry Stewart Talks, 2022. - 1 online resource (1 streaming video file (54 min.) : color, sound). - The cell division cycle : controlling when and where cells divide and differentiate, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Cell division cycle : controlling when and where cells divide and differentiate. .
Animated audio-visual presentation with synchronized narration. Title from title frames. Updated version of a talk first published in 2009.
Contents: What is chromosome biorientation and why is it important? -- Failure to bi-orient a chromosome will lead to mis-segregation/aneuploidy -- Modes of sister chromatid attachment to spindle microtubules -- The budding yeast (Saccharomyces cerevisiae) as a model for studying chromosome bi-orientation -- Monitoring sister centromeres on individual yeast chromosomes -- Kinetochore capture -- Achieving chromosome bi-orientation: mechanisms -- Geometry-dependent mechanism or a correction mechanism? -- Yeast Ipl1p kinase -- Chromosomes fail to bi-orient with high frequency in Ipl1 mutants -- How might Ipl1p kinase promote bi-orientation? -- Yeast chromosomes can bi-orient without the need for back-to-back geometry -- How does Ipl1p kinase promote bi-orientation? -- The yeast chromosomal passenger complex -- Models for tension-sensing -- What are the targets of Ipl1p kinase at the kinetochore? -- Model for Ipl1 / Aurora function in promoting bi-orientation -- Does Aurora B have similar targets in other organisms? -- Other components required for bi-orientation -- Ipl1p kinase may coordinate chromosome bi-orientation and spindle checkpoint activation.
Access restricted to subscribers.
Mode of access: World Wide Web.
2259 Henry Stewart Talks
Saccharomyces cerevisiae--Genetics.
Yeast fungi--Genetics.
Aneuploidy.
Aurora Kinases.
Cell Cycle.
Chromatids.
Chromosomes, Fungal.
Kinetochores.
Microtubules.
Saccharomyces cerevisiae--genetics.
Saccharomyces cerevisiae--physiology.
Spindle Apparatus--physiology.
Chromosome bi-orientation in yeast [electronic resource] / Mike Stark and Tomo Tanaka. - London : Henry Stewart Talks, 2022. - 1 online resource (1 streaming video file (54 min.) : color, sound). - The cell division cycle : controlling when and where cells divide and differentiate, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Cell division cycle : controlling when and where cells divide and differentiate. .
Animated audio-visual presentation with synchronized narration. Title from title frames. Updated version of a talk first published in 2009.
Contents: What is chromosome biorientation and why is it important? -- Failure to bi-orient a chromosome will lead to mis-segregation/aneuploidy -- Modes of sister chromatid attachment to spindle microtubules -- The budding yeast (Saccharomyces cerevisiae) as a model for studying chromosome bi-orientation -- Monitoring sister centromeres on individual yeast chromosomes -- Kinetochore capture -- Achieving chromosome bi-orientation: mechanisms -- Geometry-dependent mechanism or a correction mechanism? -- Yeast Ipl1p kinase -- Chromosomes fail to bi-orient with high frequency in Ipl1 mutants -- How might Ipl1p kinase promote bi-orientation? -- Yeast chromosomes can bi-orient without the need for back-to-back geometry -- How does Ipl1p kinase promote bi-orientation? -- The yeast chromosomal passenger complex -- Models for tension-sensing -- What are the targets of Ipl1p kinase at the kinetochore? -- Model for Ipl1 / Aurora function in promoting bi-orientation -- Does Aurora B have similar targets in other organisms? -- Other components required for bi-orientation -- Ipl1p kinase may coordinate chromosome bi-orientation and spindle checkpoint activation.
Access restricted to subscribers.
Mode of access: World Wide Web.
2259 Henry Stewart Talks
Saccharomyces cerevisiae--Genetics.
Yeast fungi--Genetics.
Aneuploidy.
Aurora Kinases.
Cell Cycle.
Chromatids.
Chromosomes, Fungal.
Kinetochores.
Microtubules.
Saccharomyces cerevisiae--genetics.
Saccharomyces cerevisiae--physiology.
Spindle Apparatus--physiology.