Evans, William E.
Genetic polymorphism of thiopurine methyltransferase and thiopurine therapy from molecular genetics to clinical medicine / [electronic resource] : William E. Evans. - London : Henry Stewart Talks, 2022. - 1 online resource (1 streaming video file (55 min.) : color, sound). - Cancer therapy : latest thinking in efficacy and toxicity , 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Cancer therapy : latest thinking in efficacy and toxicity. .
Animated audio-visual presentation with synchronized narration. Title from title frames. Updated version of a talk first published in 2009.
Contents: Pharmacogenomics to optimize cancer chemotherapeutics -- The genetic polymorphism of thiopurine methyltransferase (TPMT) -- Its influence on thiopurine (e.g., mercaptopurine, azathioprine) therapy -- Molecular and biochemical basis of this pharmacogenetic trait -- Clinical diagnostic widely used to individualize and optimize thiopurine therapy for cancer and other diseases -- Update talk: Hematologic toxicity of thiopurines -- Update talk: TPMT -- Update talk: NUDT15 -- Update talk: Ancestry-related differences in allele frequency.
Access restricted to subscribers.
Mode of access: World Wide Web.
2012 Henry Stewart Talks
Cancer--Chemotherapy.
Methyltransferases.
Molecular genetics.
Pharmacogenomics.
Azathioprine.
Gene Frequency.
Mercaptopurine.
Methyltransferases--genetics.
Methyltransferases--metabolism.
Molecular Biology.
Neoplasms--complications.
Neoplasms--drug therapy.
Pharmacogenetics.
Pharmacogenomic Testing.
Polymorphism, Genetic.
thiopurine methyltransferase.
Genetic polymorphism of thiopurine methyltransferase and thiopurine therapy from molecular genetics to clinical medicine / [electronic resource] : William E. Evans. - London : Henry Stewart Talks, 2022. - 1 online resource (1 streaming video file (55 min.) : color, sound). - Cancer therapy : latest thinking in efficacy and toxicity , 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Cancer therapy : latest thinking in efficacy and toxicity. .
Animated audio-visual presentation with synchronized narration. Title from title frames. Updated version of a talk first published in 2009.
Contents: Pharmacogenomics to optimize cancer chemotherapeutics -- The genetic polymorphism of thiopurine methyltransferase (TPMT) -- Its influence on thiopurine (e.g., mercaptopurine, azathioprine) therapy -- Molecular and biochemical basis of this pharmacogenetic trait -- Clinical diagnostic widely used to individualize and optimize thiopurine therapy for cancer and other diseases -- Update talk: Hematologic toxicity of thiopurines -- Update talk: TPMT -- Update talk: NUDT15 -- Update talk: Ancestry-related differences in allele frequency.
Access restricted to subscribers.
Mode of access: World Wide Web.
2012 Henry Stewart Talks
Cancer--Chemotherapy.
Methyltransferases.
Molecular genetics.
Pharmacogenomics.
Azathioprine.
Gene Frequency.
Mercaptopurine.
Methyltransferases--genetics.
Methyltransferases--metabolism.
Molecular Biology.
Neoplasms--complications.
Neoplasms--drug therapy.
Pharmacogenetics.
Pharmacogenomic Testing.
Polymorphism, Genetic.
thiopurine methyltransferase.