000			02131ngm a2200337 a 4500
001			HST2260_1_3
003			UkLoHST
006			m c
007			cr|cna|||a||||
007			vz|czazum
008			080121s2009 enk|||||||||||s|||v|eng d
028	5	0	_a2260 _bHenry Stewart Talks
035			_a(UkLoHST)1266
035			_a(UkLU-K)001103518
040			_aUkLU-K _beng _cUkLU-K
100	1		_aHardwick, Kevin G. _4spk
245	1	4	_aThe spindle checkpoint _h[electronic resource] / _cKevin G. Hardwick.
260			_aLondon : _bHenry Stewart Talks, _c2009.
300			_a1 online resource (1 streaming video file (54 min.) : _bcolor, sound).
490	1		_aThe cell division cycle : controlling when and where cells divide and differentiate, _x2056-452X
500			_aAnimated audio-visual presentation with synchronized narration.
500			_aTitle from title frames.
505	0		_aContents: Cell cycle checkpoints -- The metaphase to anaphase transition -- The spindle checkpoint -- What do cells monitor? -- Unattached kinetochores -- Lack of tension -- Checkpoint components -- Budding yeast genetic screens -- Microcolony assay -- Localisation of Mad proteins -- Checkpoint proteins are all recruited kinetochores -- Role of kinetochores -- Global signaling -- Identification of Cdc20 as the checkpoint effector -- CdC20-APC -- FRAP -- Mad1/Mad2 complex as a template -- The anaphase promoting complex (APC) -- How is anaphase onset inhibited -- Mad2 and Mad3 bind mitotic APC -- Separase regulation by securin -- Error correction -- Chromosomal passenger proteins -- How to sense a lack of tension? -- Checkpoint role(s) of Aurora kinase (Ipl1) -- Checkpoint silencing -- Disease relevance -- Future directions.
506			_aAccess restricted to subscribers.
538			_aMode of access: World Wide Web.
650		2	_aCell Cycle.
650		2	_aMitosis.
830		0	_aHenry Stewart talks. _pBiomedical & life sciences collection. _pCell division cycle : controlling when and where cells divide and differentiate.
856	4	0	_uhttps://hstalks.com/bs/1266/
856	4	2	_uhttps://hstalks.com/bs/p/381/ _3Series
999			_c78551 _d78551