000 02324cgm a2200445 a 4500
001 HST1996_1_2
003 UkLoHST
006 m c
007 cr|cna|||a||||
007 vz|czazum
008 210119s2011 enk|||||||||||s|||v|eng d
028 5 0 _a1996
_bHenry Stewart Talks
035 _a(UkLoHST)1301
040 _aUkLoHST
_beng
_cUkLoHST
100 1 _aMurray, Peter J.,
_cPh. D.
_4spk
245 1 0 _aArginase and nitric oxide
_h[electronic resource] /
_cPeter J. Murray.
260 _aLondon :
_bHenry Stewart Talks,
_c2011.
300 _a1 online resource (1 streaming video file (39 min.) :
_bcolor, sound).
490 1 _aInnate immunity : host recognition and response in health and disease,
_x2056-452X
500 _aAnimated audio-visual presentation with synchronized narration.
500 _aTitle from title frames.
500 _aUpdated version of a talk first published in 2009.
505 0 _aContents: Catabolism of arginine to downstream substrates -- Catabolism of arginine in macrophages -- Nitric oxide production -- Control of iNOS at the transcriptional level -- Role of nitric oxide in immunity to intracellular pathogens with a focus on mycobacterial disease -- Structure of arginases -- Transcriptional control of arginase 1 in the liver vs. macrophages -- Arginases can suppress nitric oxide production by substrate depletion -- Pathogens use many mechanisms to regulate nitric oxide -- Arginases and alternatively-activated macrophages (AAMs) -- Schistosome infection as an example of AAM function -- AAMs and arginases -- Arginase inhibition by small molecules -- Outstanding questions.
506 _aAccess restricted to subscribers.
538 _aMode of access: World Wide Web.
650 0 _aArginase.
650 0 _aNatural immunity.
650 0 _aNitric oxide.
650 2 _aarginase I, human.
650 2 _aArginase.
650 2 _aArginine.
650 2 _aImmunity, Innate.
650 2 _aMacrophages.
650 2 _aNitric Oxide Synthase Type II.
650 2 _aNitric Oxide.
650 2 _aNOS2 protein, human.
830 0 _aHenry Stewart talks.
_pBiomedical & life sciences collection.
_pInnate immunity : host recognition and response in health and disease.
856 4 0 _uhttps://hstalks.com/bs/1301/
856 4 2 _uhttps://hstalks.com/bs/p/437/
_3Series
999 _c78520
_d78520