000			01942ngm a2200337 a 4500
001			HST2009_1_2
003			UkLoHST
006			m c
007			cr|cna|||a||||
007			vz|czazum
008			080121s2008 enk|||||||||||s|||v|eng d
028	5	0	_a2009 _bHenry Stewart Talks
035			_a(UkLoHST)1059
035			_a(UkLU-K)000947317
040			_aUkLU-K _beng _cUkLU-K
100	1		_aHumphries, Steve E. _4spk
245	1	0	_aFamilial hyperchlolesterolaemia _h[electronic resource] : _ba monogenic cause of early CHD / _cSteve Humphries.
260			_aLondon : _bHenry Stewart Talks, _c2008.
300			_a1 online resource (1 streaming video file (50 min.) : _bcolor, sound).
490	1		_aGenetics of cardiovascular disease : genetic interactions in a multifactorial disease, _x2056-452X
500			_aAnimated audio-visual presentation with synchronized narration.
500			_aTitle from title frames.
505	0		_aContents: Clinical diagnostic criteria -- Prevalence in UK -- Effects of statins on cholesterol and CHD risk lowering -- The 3 genes where mutations cause FH (LDLR, APOB, PCSK9) -- Clinical Genetics Diagnostic service for FH and examples in families -- Cascade testing for FH patients using LDL cholesterol levels -- The Overlap problem -- The Simon Broome FH register project and the high risk of early CHD in those with an LDLR and PCSK9 mutation -- The LDLR mutation database -- Ethical issues about genetic testing for FH -- Clinical questions in the management of FH -- FH testing and insurance.
506			_aAccess restricted to subscribers.
538			_aMode of access: World Wide Web.
650		2	_aCardiovascular Diseases _xgenetics.
650		2	_aHypercholesterolemia _xgenetics.
830		0	_aHenry Stewart talks. _pBiomedical & life sciences collection. _pGenetics of cardiovascular disease.
856	4	0	_uhttps://hstalks.com/bs/1059/
856	4	2	_uhttps://hstalks.com/bs/p/379/ _3Series
999			_c78450 _d78450