000			01977ngm a2200361 a 4500
001			HST1028_1_3
003			UkLoHST
006			m c
007			cr|cna|||a||||
007			vz|czazum
008			080121s2007 enk|||||||||||s|||v|eng d
028	5	0	_a1028 _bHenry Stewart Talks
035			_a(UkLoHST)114
035			_a(UkLU-K)000963467
040			_aUkLoHST _beng _cUkLoHST
100	1		_aBird, A. P. _4spk
245	1	0	_aDNA methylation _h[electronic resource] / _cAdrian Bird.
260			_aLondon : _bHenry Stewart Talks, _c2007.
300			_a1 online resource (1 streaming video file (43 min.) : _bcolor, sound).
490	1		_aEpigenetics : concepts, theories, paradigms and mechanisms, _x2056-452X
500			_aAnimated audio-visual presentation with synchronized narration.
500			_aTitle from title frames.
505	0		_aContents: DNA methylation as an epigenetic mark -- location and patterns of methylated and nonmethylated CpG sites in the vertebrate genome -- factors determining DNA methylation patterns -- association of DNA methylation with stable gene silencing, e.g. methylation of CpG islands on the inactive X-chromosome, ensures long term repression of associated genes -- recruitment of corepressors that impose a silent chromatin structure -- repulsion of transcriptional activators by methyl-CpG leading to gene silencing -- the link between human disorders, including cancer, Rett Syndrome and ICF syndrome, and defects in the DNA methylation system.
506			_aAccess restricted to subscribers.
538			_aMode of access: World Wide Web.
650		2	_aEpigenesis, Genetic.
650		2	_aEukaryotic Cells.
650		2	_aGene Expression Regulation.
650		2	_aTranscription, Genetic.
830		0	_aHenry Stewart talks. _pBiomedical & life sciences collection. _pEpigenetics : concepts, theories, paradigms and mechanisms.
856	4	0	_uhttps://hstalks.com/bs/114/
856	4	2	_uhttps://hstalks.com/bs/p/18/ _3Series
999			_c78440 _d78440