000 | 02264ngm a2200337 a 4500 | ||
---|---|---|---|
001 | HST1911_1_2 | ||
003 | UkLoHST | ||
006 | m c | ||
007 | cr|cna|||a|||| | ||
007 | vz|czazum | ||
008 | 080121s2008 enk|||||||||||s|||v|eng d | ||
028 | 5 | 0 |
_a1911 _bHenry Stewart Talks |
035 | _a(UkLoHST)952 | ||
035 | _a(UkLU-K)AC000395881 | ||
040 |
_aUkLU-K _beng _cUkLU-K |
||
100 | 1 |
_aManson, Jean. _4spk |
|
245 | 1 | 0 |
_aPredicting TSE transmission _h[electronic resource] / _cJean Manson. |
260 |
_aLondon : _bHenry Stewart Talks, _c2008. |
||
300 |
_a1 online resource (1 streaming video file (41 min.) : _bcolor, sound). |
||
490 | 1 |
_aPrions and amyloids : self-propagating protein structures in mammals, yeast and fungi, _x2056-452X |
|
500 | _aAnimated audio-visual presentation with synchronized narration. | ||
500 | _aTitle from title frames. | ||
505 | 0 | _aContents: The TSEs continue to pose a problem to animal and human health -- The vCJD epidemic appears to be in decline but new risks of human to human transmission are now apparent -- Chronic wasting disease is a major problem currently in the US although its presence has not yet been detected in Europe -- Predicting and preventing transmission of disease requires an understanding of the routes of transmission within and between animals and the host factors which determine susceptibility -- We have studied natural disease and both in vivo and in vitro model systems to unravel the basic mechanisms of disease -- PrP protein has a central role in the outcome disease and mutations and polymorphisms in host PrP can profoundly alter the host's susceptibility to a TSE agent -- Precisely how host PrP influences the outcome of disease has not been established -- Both mutations and glycosylation can profoundly influence transmission both within and between species. | |
506 | _aAccess restricted to subscribers. | ||
538 | _aMode of access: World Wide Web. | ||
650 | 2 | _aAmyloid. | |
650 | 2 | _aPrions. | |
830 | 0 |
_aHenry Stewart talks. _pBiomedical & life sciences collection. _pPrions and amyloids : self-propagating protein structures in mammals, yeast and fungi. |
|
856 | 4 | 0 | _uhttps://hstalks.com/bs/952/ |
856 | 4 | 2 |
_uhttps://hstalks.com/bs/p/282/ _3Series |
999 |
_c78404 _d78404 |