000			01774ngm a2200325 a 4500
001			HST1741_1_3
003			UkLoHST
006			m c
007			cr|cna|||a||||
007			vz|czazum
008			080121s2007 enk|||||||||||s|||v|eng d
028	5	0	_a1741 _bHenry Stewart Talks
035			_a(UkLoHST)349
035			_a(UkLU-K)AC000392217
040			_aUkLU-K _beng _cUkLU-K
100	1		_aCyr, Douglas M. _4spk
245	1	0	_aRoles for molecular chaperones in cystic fibrosis _h[electronic resource] / _cDoug Cyr.
260			_aLondon : _bHenry Stewart Talks, _c2007.
300			_a1 online resource (1 streaming video file (53 min.) : _bcolor, sound).
490	1		_aMolecular chaperones : principles and diseases, _x2056-452X
500			_aAnimated audio-visual presentation with synchronized narration.
500			_aTitle from title frames.
505	0		_aContents: Cystic fibrosis is a fatal homozygous recessive disorder -- Caused primarily by misfolding of mutant forms of cystic fibrosis transmembrane conductance regulator (CFTR) -- The folding defects in mutant CFTR are detected by protein quality control machines in the endoplasmic reticulum that target mutant CFTR for premature degradation -- Small molecules that are being developed as drugs to treat cystic fibrosis enable mutant CFTR to avoid recognition by the endoplasmic reticulum quality control system and function at the cell surface.
506			_aAccess restricted to subscribers.
538			_aMode of access: World Wide Web.
650		2	_aMolecular Chaperones.
830		0	_aHenry Stewart talks. _pBiomedical & life sciences collection. _pMolecular chaperones : principles and diseases.
856	4	0	_uhttps://hstalks.com/bs/349/
856	4	2	_uhttps://hstalks.com/bs/p/29/ _3Series
999			_c78283 _d78283