000			02027ngm a2200373 a 4500
001			HST1384_1_2
003			UkLoHST
006			m c
007			cr|cna|||a||||
007			vz|czazum
008			080121s2007 enk|||||||||||s|||v|eng d
028	5	0	_a1384 _bHenry Stewart Talks
035			_a(UkLoHST)64
035			_a(UkLU-K)AC000392095
040			_aUkLU-K _beng _cUkLU-K
100	1		_aOlson, Steven T. _4spk
245	1	0	_aRegulation of blood coagulation by the serpin, antithrombin _h[electronic resource] / _cSteven T. Olson.
260			_aLondon : _bHenry Stewart Talks, _c2007.
300			_a1 online resource (1 streaming video file (48 min.) : _bcolor, sound).
490	1		_aProtein epidemiology : understanding human diseases at the level of protein structure and function, _x2056-452X
500			_aAnimated audio-visual presentation with synchronized narration.
500			_aTitle from title frames.
505	0		_aContents: Antithrombin and hemostasis -- Dysfunctional antithrombins and thrombophilia -- Protease regulation by serpins -- Heparin requirement for antithrombin function -- Structural determinants of heparin binding to antithrombin -- Heparin-induced conformational changes in antithrombin -- Heparin as an allosteric activator of antithrombin -- Bridging and conformational change mechanisms of heparin activation of antithrombin -- Structural basis of conformational activation -- Role of exosites in conformational activation -- Role of the reactive loop in antithrombin anticoagulant function -- Implications for improved heparin anticoagulants.
506			_aAccess restricted to subscribers.
538			_aMode of access: World Wide Web.
650		2	_aAntithrombins.
650		2	_aHemostasis.
650		2	_aProtein Conformation.
650		2	_aProteins.
650		2	_aSerpins.
830		0	_aHenry Stewart talks. _pBiomedical & life sciences collection. _pProtein epidemiology.
856	4	0	_uhttps://hstalks.com/bs/64/
856	4	2	_uhttps://hstalks.com/bs/p/33/ _3Series
999			_c78030 _d78030