| 000 | 02484ngm a2200349 a 4500 | ||
|---|---|---|---|
| 001 | HST1231_1_2 | ||
| 003 | UkLoHST | ||
| 006 | m c | ||
| 007 | cr|cna|||a|||| | ||
| 007 | vz|czazum | ||
| 008 | 080121s2007 enk|||||||||||s|||v|eng d | ||
| 028 | 5 | 0 |
_a1231 _bHenry Stewart Talks |
| 035 | _a(UkLoHST)455 | ||
| 035 | _a(UkLU-K)AC000392456 | ||
| 040 |
_aUkLU-K _beng _cUkLU-K |
||
| 100 | 1 |
_aMohammadi, Moosa. _4spk |
|
| 245 | 1 | 0 |
_aStructural basis for Fibroblast Growth Factor (FGF) receptor activation _h[electronic resource] : _bimplications in development and disease / _cMoosa Mohammadi. |
| 246 | 1 |
_iTitle from publisher's web site: _aStructural biology of FGF signaling in human development and disease |
|
| 260 |
_aLondon : _bHenry Stewart Talks, _c2007. |
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| 300 |
_a1 online resource (1 streaming video file (41 min.) : _bcolor, sound). |
||
| 490 | 1 |
_aSignal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease, _x2056-452X |
|
| 500 | _aAnimated audio-visual presentation with synchronized narration. | ||
| 500 | _aTitle from title frames. | ||
| 505 | 0 | _aContents: FGF family of ligands, and FGF receptor (FGFR) subfamily of receptor tyrosine kinase superfamily -- The roles of FGF signaling in mammalian biology and diseases -- FGFR receptor alternative splicing and its essential role in epithelial-mesenchymal signaling loop, and organogenesis -- Structural mechanism by which FGF and heparan sulfate induce FGFR dimerization and activation on the cell surface -- A working model for FGFR autoinhibition -- Structural mechanisms by which FGF-FGFR binding specificity is achieved -- Structural basis for how alternative splicing regulates ligand-binding specificity of FGFRs -- Structural basis by which ligand-dependent pathogenic mutations in FGFR lead to receptor gain-of-function in human skeletal syndromes -- Structural basis by which alternative splicing regulates patterning ability of FGF8 in the brain. | |
| 506 | _aAccess restricted to subscribers. | ||
| 538 | _aMode of access: World Wide Web. | ||
| 650 | 2 | _aReceptor Protein-Tyrosine Kinases. | |
| 650 | 2 | _aSignal Transduction. | |
| 830 | 0 |
_aHenry Stewart talks. _pBiomedical & life sciences collection. _pSignal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease. |
|
| 856 | 4 | 0 | _uhttps://hstalks.com/bs/455/ |
| 856 | 4 | 2 |
_uhttps://hstalks.com/bs/p/38/ _3Series |
| 999 |
_c77905 _d77905 |
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