000 02336ngm a2200337 a 4500
001 HST1167_1_2
003 UkLoHST
006 m c
007 cr|cna|||a||||
007 vz|czazum
008 080121s2007 enk|||||||||||s|||v|eng d
028 5 0 _a1167
_bHenry Stewart Talks
035 _a(UkLoHST)657
035 _a(UkLU-K)AC000391812
040 _aUkLU-K
_beng
_cUkLU-K
100 1 _aLu, Patrick Y.
_4spk
245 1 0 _aTherapeutic delivery of RNAi
_h[electronic resource] /
_cPatrick Y. Lu.
246 3 _aTherapeutic delivery of RNA interference
260 _aLondon :
_bHenry Stewart Talks,
_c2007.
300 _a1 online resource (1 streaming video file (37 min.) :
_bcolor, sound).
490 1 _aRNA interference : principles and applications,
_x2056-452X
500 _aAnimated audio-visual presentation with synchronized narration.
500 _aTitle from title frames.
505 0 _aContents: RNAi therapeutics development -- RNAi cellular activity -- In vivo siRNA delivery is key -- Clinically viable siRNA deliveries -- Local delivery of siRNA -- Gene silencing in tumors -- Cancer target validation in vivo -- RNAi effects in mouse brain, joints, eyes and lungs -- siRNA therapeutics in primate models -- Challenges to siRNA systemic delivery -- Systemic delivery technology -- Targeted nanoparticle siRNA delivery -- Self assembled nanoparticle -- Integrin av-beta is a validated target -- Dual-targeted therapeutic approach -- Neovasculature targeting siRNA -- Multi-targeted anti-angiogenesis -- Efficient targeted systemic delivery -- Systemic siRNA delivery to eyes -- Systemic siRNA delivery for neuroblastoma treatment -- Tumor neovasculature inhibition -- siRNA/Atelocollagen anti-tumor efficacy -- Transferrin-mediated systemic delivery -- Antibody-mediated tumor targeting -- Targeted anti-HBV activity -- RNAi effect of chol-siRNA -- PEI-mediated siRNA lung targeting -- Clinicallyviable delivery is the key for successful siRNA therapeutics.
506 _aAccess restricted to subscribers.
538 _aMode of access: World Wide Web.
650 2 _aRNA Interference.
830 0 _aHenry Stewart talks.
_pBiomedical & life sciences collection.
_pRNA interference : principles and applications.
856 4 0 _uhttps://hstalks.com/bs/657/
856 4 2 _uhttps://hstalks.com/bs/p/37/
_3Series
999 _c77854
_d77854