| 000 | 02395ngm a2200361 a 4500 | ||
|---|---|---|---|
| 001 | HST1038_1_4 | ||
| 003 | UkLoHST | ||
| 006 | m c | ||
| 007 | cr|cna|||a|||| | ||
| 007 | vz|czazum | ||
| 008 | 080121s2007 enk|||||||||||s|||v|eng d | ||
| 028 | 5 | 0 |
_a1038 _bHenry Stewart Talks |
| 035 | _a(UkLoHST)124 | ||
| 035 | _a(UkLU-K)AC000390031 | ||
| 040 |
_aUkLU-K _beng _cUkLU-K |
||
| 100 | 1 |
_aBaylin, Stephen B. _4spk |
|
| 245 | 1 | 0 |
_aEpigenetically mediated gene silencing _h[electronic resource] : _ba companion to genetic alterations in driving tumorigenesis / _cStephen Baylin. |
| 246 | 3 |
_aEpigenetically mediated gene silencing : _btumorigenesis |
|
| 260 |
_aLondon : _bHenry Stewart Talks, _c2007. |
||
| 300 |
_a1 online resource (1 streaming video file (68 min.) : _bcolor, sound). |
||
| 490 | 1 |
_aEpigenetics : concepts, theories, paradigms and mechanisms, _x2056-452X |
|
| 500 | _aAnimated audio-visual presentation with synchronized narration. | ||
| 500 | _aTitle from title frames. | ||
| 505 | 0 | _aContents: Introduction to epigenetic changes in cancer -- defining the process of promoter DNA hypermethylation as a constituent of a broad range of chromatin abnormalities in cancer -- defining the genes aberrantly silenced in cancer including approaches being used to screen the cancer genome for such genes -- defining what is known about the interaction of DNA methylation and chromatin modifications for initiating and maintaining gene silencing in cancer -- outlining the position of aberrant gene silencing in tumor progression and particularly highlighting the key role these changes may play for the earliest steps in tumorigenesis -- defining the potential for using DNA hypermethylated gene promoter sequences as molecular markers for cancer risk assessment, early diagnosis and prognosis -- discussing the possibilities for targeting reversal of gene silencing as a prevention and therapeutic strategy for cancer. | |
| 506 | _aAccess restricted to subscribers. | ||
| 538 | _aMode of access: World Wide Web. | ||
| 650 | 2 | _aEpigenesis, Genetic. | |
| 650 | 2 | _aGene Expression Regulation, Neoplastic. | |
| 650 | 2 | _aGene Silencing. | |
| 830 | 0 |
_aHenry Stewart talks. _pBiomedical & life sciences collection. _pEpigenetics : concepts, theories, paradigms and mechanisms. |
|
| 856 | 4 | 0 | _uhttps://hstalks.com/bs/124/ |
| 856 | 4 | 2 |
_uhttps://hstalks.com/bs/p/18/ _3Series |
| 999 |
_c77774 _d77774 |
||