000 02320ngm a2200445 a 4500
001 HST3700
003 UkLoHST
006 m c
007 cr|cna|||a||||
007 vz|czazum
008 140422s2014 enk|||||||||||s|||v|eng d
028 5 0 _a3700
_bHenry Stewart Talks
035 _a(UkLoHST)2753
040 _aUkLoHST
_beng
_cUkLoHST
100 1 _aShilatifard, Ali,
_u(Stowers Institute, USA)
_4spk
245 1 0 _aEnhancer malfunction in cancer
_h[electronic resource] /
_cAli Shilatifard.
260 _aLondon :
_bHenry Stewart Talks,
_c2014.
300 _a1 online resource (1 streaming video file (41 min.) :
_bcolor, sound).
490 1 _aEpigenetics, chromatin, transcription and cancer,
_x2056-452X
500 _aAnimated audio-visual presentation with synchronized narration.
500 _aTitle from title frames.
505 0 _aContents: MLL genes and their pathogenic translocations -- Yeast, mammalian and Drosophila systems for studying leukaemia pathogenesis -- Proteins and protein complexes that regulate chromatin modifications, transcription initiation, and transcription elongation -- What is the function of MLL? -- Why do translocations of MLL with so many different partners result in leukemogenesis? -- The AFF4 complex and Hox genes -- COMPASS family of H3K4 methylases and their mutations in cancer -- Chromatin Bivalency -- The ELL family of Pol II elongation factors -- Drosophila Trr -- Enhancer/promoter interactions, malfunctions and their outcomes.
506 _aAccess restricted to subscribers.
538 _aMode of access: World Wide Web.
650 0 _aCancer cells.
650 0 _aChromatin.
650 0 _aGenetic regulation.
650 0 _aLeukemia
_xGenetic aspects.
650 2 _aCell Transformation, Neoplastic.
650 2 _aChromatin
_xgenetics.
650 2 _aGene Expression Regulation.
650 2 _aHistone-Lysine N-Methyltransferase.
650 2 _aLeukemia
_xgenetics.
650 2 _aMyeloid-Lymphoid Leukemia Protein.
650 2 _aNeoplasms
_xgenetics.
650 2 _aTranscriptional Elongation Factors
_xmetabolism.
830 0 _aHenry Stewart talks.
_pBiomedical & life sciences collection.
_pEpigenetics, chromatin, transcription and cancer.
856 4 0 _uhttps://hstalks.com/bs/2753/
856 4 2 _uhttps://hstalks.com/bs/p/685/
_3Series
999 _c77080
_d77080