000 02293ngm a2200457 a 4500
001 HST4777
003 UkLoHST
006 m c
007 cr|cna|||a||||
007 vz|czazum
008 190805s2019 enk|||||||||||s|||v|eng d
028 5 0 _a4777
_bHenry Stewart Talks
035 _a(UkLoHST)4009
040 _aUkLoHST
_beng
_cUkLoHST
100 1 _aFan, Qing R.,
_u(Columbia University, USA)
_4spk
245 1 0 _aExtracellular domain structures from calcium-sensing and GABA(B) receptors
_h[electronic resource] /
_cQing R. Fan.
260 _aLondon :
_bHenry Stewart Talks,
_c2019.
300 _a1 online resource (1 streaming video file (36 min.) :
_bcolor, sound).
490 1 _aG Protein-Coupled Receptors (GPCRs) signaling in health and disease,
_x2056-452X
500 _aAnimated audio-visual presentation with synchronized narration.
500 _aTitle from title frames.
505 0 _aContents: Crystal structures of human GABA(B) receptor extracellular domain in multiple functional states -- Agonist vs. antagonist recognition -- Identification of novel heterodimer interface associated with receptor activation -- Crystal structures of human CaSR in the inactive and active conformations -- Discovery of L-amino acids as orthosteric agonists of CaSR -- Identification of Ca2+ and PO43 binding sites in CaSR -- Universal activation mechanism of class C GPCRs.
506 _aAccess restricted to subscribers.
538 _aMode of access: World Wide Web.
650 0 _aAmino acids
_xReceptors.
650 0 _aCalcium
_xReceptors.
650 0 _aCellular signal transduction.
650 0 _aG proteins
_xReceptors.
650 2 _aBinding Sites.
650 2 _aGABA-B Receptor Agonists.
650 2 _aGABA-B Receptor Antagonists.
650 2 _aProtein Conformation.
650 2 _aReceptors, Calcium-Sensing
_xchemistry.
650 2 _aReceptors, Calcium-Sensing
_xmetabolism.
650 2 _aReceptors, GABA-B
_xchemistry.
650 2 _aReceptors, GABA-B
_xmetabolism.
650 2 _aReceptors, G-Protein-Coupled.
830 0 _aHenry Stewart talks.
_pBiomedical & life sciences collection.
_pG Protein-Coupled Receptors (GPCRs) signaling in health and disease.
856 4 0 _uhttps://hstalks.com/bs/4009/
856 4 2 _uhttps://hstalks.com/bs/p/1083/
_3Series
999 _c76184
_d76184