000 01777ngm a2200397 a 4500
001 HST5267
003 UkLoHST
006 m c
007 cr|cna|||a||||
007 vz|czazum
008 210404s2021 enk|||||||||||s|||v|eng d
028 5 0 _a5267
_bHenry Stewart Talks
035 _a(UkLoHST)4547
040 _aUkLoHST
_beng
_cUkLoHST
100 1 _aLerchen, Hans-Georg,
_u(Bayer AG, Germany)
_4spk
245 1 0 _aDevelopment of antibody prodrug conjugates activated by legumain
_h[electronic resource] /
_cHans-Georg Lerchen.
260 _aLondon :
_bHenry Stewart Talks,
_c2021.
300 _a1 online resource (1 streaming video file (35 min.) :
_bcolor, sound).
490 1 _aThe biomedical & life sciences collection,
_x2056-452X
500 _aAnimated audio-visual presentation with synchronized narration.
500 _aTitle from title frames.
505 0 _aContents: Modular composition of antibody drug conjugates -- ADC mode of action -- TWEAK receptor as an ADC target -- Improvements to achieve stable antibody conjugation -- KSP inhibitors as ADC toxophores -- Legumain-cleavable antibody prodrug conjugates -- Conceptualization of Antibody Prodrug Conjugates (APDCs) to increase the therapeutic window.
506 _aAccess restricted to subscribers.
538 _aMode of access: World Wide Web.
650 0 _aAntibody-drug conjugates.
650 0 _aDrug development.
650 2 _aAntibodies, Monoclonal.
650 2 _aAntineoplastic Agents.
650 2 _aasparaginylendopeptidase.
650 2 _aCysteine Endopeptidases.
650 2 _aImmunoconjugates.
650 2 _aProdrugs.
650 2 _aTWEAK Receptor.
830 0 _aHenry Stewart talks.
_pBiomedical & life sciences collection.
856 4 0 _uhttps://hstalks.com/bs/4547/
999 _c75806
_d75806