| 000 | 02488cgm a2200505 a 4500 | ||
|---|---|---|---|
| 001 | HST2012_1_3 | ||
| 003 | UkLoHST | ||
| 006 | m c | ||
| 007 | cr|cna|||a|||| | ||
| 007 | vz|czazum | ||
| 008 | 220904s2022 enk|||||||||||s|||v|eng d | ||
| 028 | 5 | 0 |
_a2012 _bHenry Stewart Talks |
| 035 | _a(UkLoHST)1121 | ||
| 040 |
_aUkLoHST _beng _cUkLoHST |
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| 100 | 1 |
_aEvans, William E. _4spk |
|
| 245 | 1 | 0 |
_aGenetic polymorphism of thiopurine methyltransferase and thiopurine therapy _h[electronic resource] : _bfrom molecular genetics to clinical medicine / _cWilliam E. Evans. |
| 260 |
_aLondon : _bHenry Stewart Talks, _c2022. |
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| 300 |
_a1 online resource (1 streaming video file (55 min.) : _bcolor, sound). |
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| 490 | 1 |
_aCancer therapy : latest thinking in efficacy and toxicity , _x2056-452X |
|
| 500 | _aAnimated audio-visual presentation with synchronized narration. | ||
| 500 | _aTitle from title frames. | ||
| 500 | _aUpdated version of a talk first published in 2009. | ||
| 505 | 0 | _aContents: Pharmacogenomics to optimize cancer chemotherapeutics -- The genetic polymorphism of thiopurine methyltransferase (TPMT) -- Its influence on thiopurine (e.g., mercaptopurine, azathioprine) therapy -- Molecular and biochemical basis of this pharmacogenetic trait -- Clinical diagnostic widely used to individualize and optimize thiopurine therapy for cancer and other diseases -- Update talk: Hematologic toxicity of thiopurines -- Update talk: TPMT -- Update talk: NUDT15 -- Update talk: Ancestry-related differences in allele frequency. | |
| 506 | _aAccess restricted to subscribers. | ||
| 538 | _aMode of access: World Wide Web. | ||
| 650 | 0 |
_aCancer _xChemotherapy. |
|
| 650 | 0 | _aMethyltransferases. | |
| 650 | 0 | _aMolecular genetics. | |
| 650 | 0 | _aPharmacogenomics. | |
| 650 | 2 | _aAzathioprine. | |
| 650 | 2 | _aGene Frequency. | |
| 650 | 2 | _aMercaptopurine. | |
| 650 | 2 |
_aMethyltransferases _xgenetics. |
|
| 650 | 2 |
_aMethyltransferases _xmetabolism. |
|
| 650 | 2 | _aMolecular Biology. | |
| 650 | 2 |
_aNeoplasms _xcomplications. |
|
| 650 | 2 |
_aNeoplasms _xdrug therapy. |
|
| 650 | 2 | _aPharmacogenetics. | |
| 650 | 2 | _aPharmacogenomic Testing. | |
| 650 | 2 | _aPolymorphism, Genetic. | |
| 650 | 2 | _athiopurine methyltransferase. | |
| 830 | 0 |
_aHenry Stewart talks. _pBiomedical & life sciences collection. _pCancer therapy : latest thinking in efficacy and toxicity. |
|
| 856 | 4 | 0 | _uhttps://hstalks.com/bs/1121/ |
| 856 | 4 | 2 |
_uhttps://hstalks.com/bs/p/385/ _3Series |
| 999 |
_c75500 _d75500 |
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