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001			9780429469893
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005			20220531132449.0
006			m o d
007			cr |n|||||||||
008			201119s2020 xx o 0|| 0 eng d
040			_aOCoLC-P _beng _cOCoLC-P
020			_a9780429892127 _q(electronic bk.)
020			_a0429892128 _q(electronic bk.)
020			_a9780429892134 _q(e-book)
020			_a0429892136
020			_a9780429469893 _q(electronic bk.)
020			_a0429469896 _q(electronic bk.)
020			_a9780429892110 _q(electronic bk. : Mobipocket)
020			_a042989211X _q(electronic bk. : Mobipocket)
020			_z1138598984
020			_z9781138598980
024	7		_a10.1201/9780429469893 _2doi
035			_a(OCoLC)1222895353 _z(OCoLC)1228888849 _z(OCoLC)1230537542
035			_a(OCoLC-P)1222895353
050		4	_aR857.O6
072		7	_aMED _x009000 _2bisacsh
072		7	_aSCI _x047000 _2bisacsh
072		7	_aSCI _x055000 _2bisacsh
072		7	_aMQW _2bicssc
082	0	4	_a570.28 _223
100	1		_aOber, Raimund J.
245	1	0	_aQUANTITATIVE BIOIMAGING _h[electronic resource] : _ban introduction to biology, instrumentation, experiments, and data... analysis for scientists and engineers.
260			_a[S.l.] : _bCRC PRESS, _c2020.
300			_a1 online resource
336			_atext _2rdacontent
336			_astill image _2rdacontent
337			_acomputer _2rdamedia
338			_aonline resource _2rdacarrier
520			_aQuantitative bioimaging is a broad interdisciplinary field that exploits tools from biology, chemistry, optics, and statistical data analysis for the design and implementation of investigations of biological processes. Instead of adopting the traditional approach of focusing on just one of the component disciplines, this textbook provides a unique introduction to quantitative bioimaging that presents all of the disciplines in an integrated manner. The wide range of topics covered include basic concepts in molecular and cellular biology, relevant aspects of antibody technology, instrumentation and experimental design in fluorescence microscopy, introductory geometrical optics and diffraction theory, and parameter estimation and information theory for the analysis of stochastic data. Key Features: Comprises four parts, the first of which provides an overview of the topics that are developed from fundamental principles to more advanced levels in the other parts. Presents in the second part an in-depth introduction to the relevant background in molecular and cellular biology and in physical chemistry, which should be particularly useful for students without a formal background in these subjects. Provides in the third part a detailed treatment of microscopy techniques and optics, again starting from basic principles. Introduces in the fourth part modern statistical approaches to the determination of parameters of interest from microscopy data, in particular data generated by single molecule microscopy experiments. Uses two topics related to protein trafficking (transferrin trafficking and FcRn-mediated antibody trafficking) throughout the text to motivate and illustrate microscopy techniques. An online appendix providing the background and derivations for various mathematical results presented or used in the text is available at http://www.routledge.com/9781138598980.
588			_aOCLC-licensed vendor bibliographic record.
650		0	_aImaging systems in biology.
650		0	_aBioinformatics.
650		0	_aComputational biology.
650		7	_aMEDICAL / Biotechnology _2bisacsh
650		7	_aSCIENCE / Microscopes & Microscopy _2bisacsh
650		7	_aSCIENCE / Physics _2bisacsh
700	1		_aWard, E. Sally.
700	1		_aChao, Jerry.
856	4	0	_3Taylor & Francis _uhttps://www.taylorfrancis.com/books/9780429469893
856	4	2	_3OCLC metadata license agreement _uhttp://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf
999			_c72696 _d72696