000 | 03066nam a2200541Ii 4500 | ||
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001 | 9780429433252 | ||
003 | FlBoTFG | ||
005 | 20220531132402.0 | ||
006 | m d | ||
007 | cr un||||uuuuu | ||
008 | 190103s2019 flu fob 001 0 eng d | ||
040 |
_aOCoLC-P _beng _erda _epn _cOCoLC-P |
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020 |
_a9780429433252 _q(electronic bk.) |
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020 |
_a0429433255 _q(electronic bk.) |
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_a9780429781421 _q(electronic bk. : Mobipocket) |
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_a0429781423 _q(electronic bk. : Mobipocket) |
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_a9780429781438 _q(electronic bk. : EPUB) |
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_a0429781431 _q(electronic bk. : EPUB) |
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_a9780429781445 _q(electronic bk. : PDF) |
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020 |
_a042978144X _q(electronic bk. : PDF) |
||
020 | _z9781138360167 | ||
024 | 3 | _a9780429433252 | |
035 | _a(OCoLC)1080641987 | ||
035 | _a(OCoLC-P)1080641987 | ||
050 | 4 |
_aRC802 _b.T692 2019eb |
|
072 | 7 |
_aMED _x096000 _2bisacsh |
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072 | 7 |
_aMED _x031000 _2bisacsh |
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_aMED _x071000 _2bisacsh |
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_aPSBT _2bicssc |
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_a616.99/433 _223 |
245 | 0 | 0 |
_aToxicology of the gastrointestinal tract / _cedited by Shayne C. Gad. |
250 | _aSecond edition. | ||
264 | 1 |
_aBoca Raton, FL : _bCRC Press, _c2019. |
|
300 | _a1 online resource. | ||
336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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520 | _aThe gastrointestinal tract is the most important of the three major routes of entry (and clearance) of xenobiotics and biologic entities into the bodies of mammals. As such, it is also the major route for administration of pharmaceuticals to humans. Gastrointestinal Toxicology, Second Edition describes the mechanism for entry and clearance of xenobiotics, as well as the barriers, immunologic and metabolic issues, and functions present in the GI tract. Appearing in this volume are also considerations of the microbiome and its actions and influence on the function of the GI tract and on the toxicity and pharmacodynamics of ingested substances (including nutrients, toxins, and therapeutics). These fifteen chapters written by experienced experts in the field address methods to evaluate GI function; specifics of GI function and toxicity assessment in canines and minipigs; classes of compounds with their toxicity; species differences; and the toxicity (and promise) of nanoparticles. Those needing to understand the structure, function, and methods of studying the GI tract will find this volume a singular source of reference. | ||
588 | _aOCLC-licensed vendor bibliographic record. | ||
650 | 7 |
_aMEDICAL / Toxicology _2bisacsh |
|
650 | 7 |
_aMEDICAL / Gastroenterology _2bisacsh |
|
650 | 7 |
_aMEDICAL / Pharmacology _2bisacsh |
|
650 | 0 |
_aGastrointestinal system _xPathophysiology. |
|
650 | 0 | _aToxicology. | |
700 | 1 |
_aGad, Shayne C., _d1948- _eeditor. |
|
856 | 4 | 0 |
_3Taylor & Francis _uhttps://www.taylorfrancis.com/books/9780429433252 |
856 | 4 | 2 |
_3OCLC metadata license agreement _uhttp://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf |
999 |
_c71624 _d71624 |