000 03066nam a2200541Ii 4500
001 9780429433252
003 FlBoTFG
005 20220531132402.0
006 m d
007 cr un||||uuuuu
008 190103s2019 flu fob 001 0 eng d
040 _aOCoLC-P
_beng
_erda
_epn
_cOCoLC-P
020 _a9780429433252
_q(electronic bk.)
020 _a0429433255
_q(electronic bk.)
020 _a9780429781421
_q(electronic bk. : Mobipocket)
020 _a0429781423
_q(electronic bk. : Mobipocket)
020 _a9780429781438
_q(electronic bk. : EPUB)
020 _a0429781431
_q(electronic bk. : EPUB)
020 _a9780429781445
_q(electronic bk. : PDF)
020 _a042978144X
_q(electronic bk. : PDF)
020 _z9781138360167
024 3 _a9780429433252
035 _a(OCoLC)1080641987
035 _a(OCoLC-P)1080641987
050 4 _aRC802
_b.T692 2019eb
072 7 _aMED
_x096000
_2bisacsh
072 7 _aMED
_x031000
_2bisacsh
072 7 _aMED
_x071000
_2bisacsh
072 7 _aPSBT
_2bicssc
082 0 4 _a616.99/433
_223
245 0 0 _aToxicology of the gastrointestinal tract /
_cedited by Shayne C. Gad.
250 _aSecond edition.
264 1 _aBoca Raton, FL :
_bCRC Press,
_c2019.
300 _a1 online resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
520 _aThe gastrointestinal tract is the most important of the three major routes of entry (and clearance) of xenobiotics and biologic entities into the bodies of mammals. As such, it is also the major route for administration of pharmaceuticals to humans. Gastrointestinal Toxicology, Second Edition describes the mechanism for entry and clearance of xenobiotics, as well as the barriers, immunologic and metabolic issues, and functions present in the GI tract. Appearing in this volume are also considerations of the microbiome and its actions and influence on the function of the GI tract and on the toxicity and pharmacodynamics of ingested substances (including nutrients, toxins, and therapeutics). These fifteen chapters written by experienced experts in the field address methods to evaluate GI function; specifics of GI function and toxicity assessment in canines and minipigs; classes of compounds with their toxicity; species differences; and the toxicity (and promise) of nanoparticles. Those needing to understand the structure, function, and methods of studying the GI tract will find this volume a singular source of reference.
588 _aOCLC-licensed vendor bibliographic record.
650 7 _aMEDICAL / Toxicology
_2bisacsh
650 7 _aMEDICAL / Gastroenterology
_2bisacsh
650 7 _aMEDICAL / Pharmacology
_2bisacsh
650 0 _aGastrointestinal system
_xPathophysiology.
650 0 _aToxicology.
700 1 _aGad, Shayne C.,
_d1948-
_eeditor.
856 4 0 _3Taylor & Francis
_uhttps://www.taylorfrancis.com/books/9780429433252
856 4 2 _3OCLC metadata license agreement
_uhttp://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf
999 _c71624
_d71624