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040 _aOCoLC-P
_beng
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_epn
_cOCoLC-P
020 _a9780429155826
_q(electronic bk.)
020 _a0429155824
_q(electronic bk.)
020 _a9780429546549
_q(electronic bk. : Mobipocket)
020 _a0429546548
_q(electronic bk. : Mobipocket)
020 _a9781498761314
_q(electronic bk. : PDF)
020 _a1498761313
_q(electronic bk. : PDF)
020 _a9780429531842
_q(electronic bk. : EPUB)
020 _a0429531842
_q(electronic bk. : EPUB)
020 _z9781498761307
035 _a(OCoLC)1104836029
035 _a(OCoLC-P)1104836029
050 4 _aRC270.8
072 7 _aHEA
_x039000
_2bisacsh
072 7 _aMED
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_2bisacsh
072 7 _aMED
_x022000
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072 7 _aMED
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072 7 _aMED
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072 7 _aMAT
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072 7 _aMED
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072 7 _aMBNS
_2bicssc
082 0 4 _a616.99406
_223
100 1 _aKhan, Iftekhar
_c(Statistician),
_eauthor.
245 1 0 _aEconomic evaluation of cancer drugs :
_busing clinical trial and real-world data /
_cIftekhar Khan, Ralph Crott, and Zahid Bashir.
264 1 _aBoca Raton :
_bCRC Press,
_c[2020]
264 4 _c©2020
300 _a1 online resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
490 1 _aChapman & Hall/CRC biostatistics series
520 _aCancer is a major healthcare burden across the world and impacts not only the people diagnosed with various cancers but also their families, carers, and healthcare systems. With advances in the diagnosis and treatment, more people are diagnosed early and receive treatments for a disease where few treatments options were previously available. As a result, the survival of patients with cancer has steadily improved and, in most cases, patients who are not cured may receive multiple lines of treatment, often with financial consequences for the patients, insurers and healthcare systems. Although many books exist that address economic evaluation, Economic Evaluation of Cancer Drugs using Clinical Trial and Real World Data is the first unified text that specifically addresses the economic evaluation of cancer drugs. The authors discuss how to perform cost-effectiveness analyses while emphasising the strategic importance of designing cost-effectiveness into cancer trials and building robust economic evaluation models that have a higher chance of reimbursement if truly cost-effective. They cover the use of real-world data using cancer registries and discuss how such data can support or complement clinical trials with limited follow up. Lessons learned from failed reimbursement attempts, factors predictive of successful reimbursement and the different payer requirements across major countries including US, Australia, Canada, UK, Germany, France and Italy are also discussed. The book includes many detailed practical examples, case studies and thought-provoking exercises for use in classroom and seminar discussions. Iftekhar Khan is a medical statistician and health economist and a lead statistician at Oxford Unviersity's Center for Statistics in Medicine. Professor Khan is also a Senior Research Fellow in Health Economics at University of Warwick and is a Senior Statistical Assessor within the Licensing Division of the UK Medicine and Health Regulation Agency. Ralph Crott is a former professor in Pharmacoeconomics at the University of Montreal in Quebec, Canada and former head of the EORTC Health Economics Unit and former senior health economist at the Belgian HTA organization. Zahid Bashir has over twelve years experience working in the pharmaceutical industry in medical affairs and oncology drug development where he is involved in the design and execution of oncology clinical trials and development of reimbursement dossiers for HTA submission.
588 _aOCLC-licensed vendor bibliographic record.
650 0 _aCancer
_xTreatment
_xEconomic aspects.
650 0 _aPharmaceutical industry.
650 7 _aHEALTH & FITNESS / Diseases / General.
_2bisacsh
650 7 _aMEDICAL / Clinical Medicine.
_2bisacsh
650 7 _aMEDICAL / Diseases.
_2bisacsh
650 7 _aMEDICAL / Evidence-Based Medicine.
_2bisacsh
650 7 _aMEDICAL / Internal Medicine.
_2bisacsh
650 7 _aMATHEMATICS / Probability & Statistics / General
_2bisacsh
650 7 _aMEDICAL / Epidemiology
_2bisacsh
650 7 _aMEDICAL / Pharmacology
_2bisacsh
700 1 _aCrott, Ralph,
_eauthor.
700 1 _aBashir, Zahid,
_eauthor.
856 4 0 _3Taylor & Francis
_uhttps://www.taylorfrancis.com/books/9780429155826
856 4 2 _3OCLC metadata license agreement
_uhttp://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf
999 _c71396
_d71396