Cytoplasmic innate immune sensors [electronic resource] / Seth Masters.
Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Cells of the innate immune system: Publisher: London : Henry Stewart Talks, 2019Description: 1 online resource (1 streaming video file (58 min.) : color, sound)Subject(s): Cytoplasm | Immune system | Inflammation -- Pathophysiology | Natural immunity | Adaptive Immunity | Autoimmunity | cyclic guanosine monophosphate-adenosine monophosphate | Cytoplasm -- immunology | Cytoplasm -- metabolism | Immunity, Innate | Inflammasomes -- immunology | MB21D1 protein, human | Nucleotides, Cyclic | Nucleotidyltransferases | Pathogen-Associated Molecular Pattern MoleculesOnline resources: Click here to access online | SeriesAnimated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Introduction to the Adaptive vs. Innate Immune system -- Autoimmunity vs. Autoinflammatory disease -- Cytoplasmic innate immune sensors -- NLRs and the inflammasome -- NLRP3 inflammasome -- Pyrin inflammasome -- NLRC4 inflammasome -- NLRP1 inflammasome -- NOD1 and NOD2 -- RLRs and detection of cytoplasmic RNA/DNA -- DNA sensing by cGAS and AIM2 -- RNA sensing by Rig-I and MDA-5 -- Programmed inflammatory cell death -- Spreading the signal (cGAMP and Inflammasomes) -- PAMPs, DAMPs and HAMPs.
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Mode of access: World Wide Web.