RNAi for neurological diseases [electronic resource] / Beverly L. Davidson.
Material type:![Film](/opac-tmpl/lib/famfamfam/VM.png)
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Repeat expansion diseases -- Polyglutamine (polyQ) repeat diseases -- Huntington's disease -- Vectors for delivering genetic material to brain -- AAVs for delivering RNAi for reducing gene expression -- Artificial miRNAs -- Testing miHD for efficacy -- Off-target silencing -- MRI-guided delivery of AAV into primates -- HTT suppression -- Other gain-of function diseases -- Targeted infusion for broad coverage -- Silencing ataxin-1 -- Nonallele specific silencing: experimental design -- Expression and activity of miSCA1.
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Mode of access: World Wide Web.