The predominant clonal evolution (PCE) concept of microbial pathogens and its practical usefulness [electronic resource] / Michel Tibayrenc.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Using bioinformatics in the exploration of genetic diversity : fundamentals and recent advances: Publisher: London : Henry Stewart Talks, 2018Description: 1 online resource (1 streaming video file (29 min.) : color, sound)Subject(s): Evolution (Biology) | Evolutionary genetics | Pathogenic microorganisms -- Genetics | Adaptation, Physiological | Bacteria -- genetics | Clonal Evolution | Dysequilibrium Syndrome | Epidemiology, Molecular | Fungi -- genetics | Genetic Variation | Linkage Disequilibrium | Multilocus Sequence Typing | Parasites -- genetics | Recombination, Genetic | Viruses -- geneticsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Updated version of a talk first published in 2007 under the title: Molecular epidemiology and evolutionary genetics of pathogens.
Contents: Recombination vs. clonality -- Neo-Pasteurian era -- Looking for the common denominator among parasitic protozoa, fungi, bacteria and viruses -- PCE = salami slicing model -- No PCE – frequent recombination: soup model -- Recombinational load -- The PCE concept -- Linkage disequilibrium: restrained recombination -- Near-clading -- Parity between phylogenetic trees -- Multilocus Sequence Typing (MLST) -- The "Russian doll" model -- Practical implications of the PCE approach -- The clonet concept -- Revisiting the phylogenetic species concept (PSC) -- Applying the PCE approach to a given species.
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Mode of access: World Wide Web.