Lysosome [electronic resource] : much more than a degradative organelle / Diego Medina.

By: Medina, Diego [spk]Material type: FilmFilmSeries: Henry Stewart talksBiomedical & life sciences collection. Autophagy and lysosomal storage diseases: Publisher: London : Henry Stewart Talks, 2018Description: 1 online resource (1 streaming video file (17 min.) : color, sound)Subject(s): Calcium -- Physiological effect | Cell death | Cellular signal transduction | Lysosomal storage diseases | Lysosomes | Autophagy -- physiology | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors -- metabolism | Calcium Channels | Cytoplasm -- metabolism | Gene Expression Regulation | Lysosomal Storage Diseases | Lysosomes -- metabolism | Phosphorylation | Protein Transport | Transcription, Genetic | Transient Receptor Potential ChannelsOnline resources: Click here to access online | Series
Contents:
Contents: Lysosome as degradative organelle -- Transcriptional regulation of lysosomal and autophagic function -- Promoting clearance through overexpression of TFEB in lysosomal storage disorders -- TFEB regulation by phosphorylation -- Imaging approaches to identify phosphatase regulating TFEB nuclear translocation -- Role of the lysosomal calcium channel TRPML1 in TFEB nuclear translocation.
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Animated audio-visual presentation with synchronized narration.

Title from title frames.

Contents: Lysosome as degradative organelle -- Transcriptional regulation of lysosomal and autophagic function -- Promoting clearance through overexpression of TFEB in lysosomal storage disorders -- TFEB regulation by phosphorylation -- Imaging approaches to identify phosphatase regulating TFEB nuclear translocation -- Role of the lysosomal calcium channel TRPML1 in TFEB nuclear translocation.

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