Cellular and molecular toxicology [electronic resource] / Dominic Williams.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Non-clinical testing for toxicity of pharmaceuticals: Publisher: London : Henry Stewart Talks, 2009Description: 1 online resource (1 streaming video file (56 min.) : color, sound)Subject(s): Drug Toxicity | Toxicity TestsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchonized narration.
Title from title frames.
Contents: Classification of adverse drug reactions -- How this relates to the chemical structure of the offending drug -- Understanding how variation in drug metabolism can contribute to clinical toxicity is important in designing pre-clinical models and screens -- Case studies of drugs which can form reactive metabolites and can irreversibly modify cellular protein -- Examples of structural modifications to chemicals containing toxicophores -- Novel and traditional serum and cellular biomarkers of adaptation, apoptosis and necrosis.
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Mode of access: World Wide Web.