Postsynaptic scaffold proteins in health and disease [electronic resource] / Jonathan Hanley.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Synapses, neurotransmitters and receptor channels: Publisher: London : Henry Stewart Talks, 2014Description: 1 online resource (1 streaming video file (48 min.) : color, sound)Subject(s): Brain -- Diseases -- Pathophysiology | Neuronal plasticity | Protein-protein interactions | Synapses -- Physiology | Synaptic transmission -- Physiology | Brain Diseases -- physiopathology | Nerve Tissue Proteins -- metabolism | Neuronal Plasticity -- physiology | Synapses -- physiology | Synaptic Transmission -- physiologyOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Multi-domain structure of scaffold proteins allows multiple protein-protein interactions -- They localise important signaling proteins close to neurotransmitter receptor complexes -- Scaffold proteins at excitatory synapses underpin synaptic plasticity by regulating AMPA receptor trafficking and dendritic spine morphology -- Mutations in scaffold proteins underlie neuropsychiatric diseases such as autism and schizophrenia -- Other diseases including Alzheimers and stroke also involve mechanisms incorporating postsynaptic scaffold proteins.
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Mode of access: World Wide Web.