DNA replication [electronic resource] / Smita Patel.
Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (25 min.) : color, sound)Subject(s): DNA replication | Protein-protein interactions | Adenosine Triphosphatases | Bacteriophage T7 | DNA Replication | DNA -- chemistry | DNA -- genetics | DNA-Directed DNA Polymerase | Proteins -- metabolismOnline resources: Click here to access online | SeriesAnimated audio-visual presentation with synchronized narration.
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Contents: Chemical composition of DNA -- Chargaff's rule -- DNA structure -- Base pairing -- Semiconservative DNA replication -- Mechanism of DNA replication -- Semi-discontinuous DNA replication -- DNA replication is catalyzed by the cooperative action of a number of proteins: what we know -- DNA polymerase structure -- Structure of phage T7 DNA polymerase -- Chemical reaction catalyzed by DNA polymerases -- Metal ions play an essential role in DNA synthesis -- DNA synthesis has to be efficient and accurate -- Rates of correct and incorrect nucleotide addition -- How are errors corrected? -- Fidelity: exonuclease activity -- Fidelity of DNA synthesis -- Processivity of the DNA polymerase -- Processivity factors -- DNA unwinding: helicase protein -- Mechanism of double helical DNA strand separation -- Mechanism of ATPase and DNA translocation -- Helicase functions in conjunction with the DNA polymerase -- Synergy between the replication proteins in catalyzing DNA replication -- Primers for DNA replication -- Properties of the DNA primase.
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Mode of access: World Wide Web.