Protein folding inside the cell [electronic resource] : macromolecular crowding and protein aggregation / R. John Ellis.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Protein folding, aggregation and design : concepts, experiments, theories and mechanisms: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (42 min.) : color, sound)Subject(s): Macromolecular Substances | Molecular Chaperones | Protein Conformation | Protein Folding | ProteinsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: The principle of protein self-assembly -- Discovery of proteins binding to newly synthesized polypeptides -- Discovery of the chaperonins -- Origins of the molecular chaperone concept -- Replacement of spontaneous self-assembly by assisted self-assembly -- Protein aggregation as a universal cellular problem -- Macromolecular crowding and its effects on reaction rates and association constants -- Stimulation of aggregation by crowding -- How chaperones combat aggregation -- Definition of molecular chaperones -- The chaperone function.
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Mode of access: World Wide Web.