SMAD phosphorylation and the TGF-beta pathway [electronic resource] / Joan Massagué.

By: Massagué, Joan, 1953- [spk]Material type: FilmFilmSeries: Henry Stewart talksBiomedical & life sciences collection. Molecular basis of cancer: ; Henry Stewart talksBiomedical & life sciences collection. Protein phosphorylation: Publisher: London : Henry Stewart Talks, 2010Description: 1 online resource (1 streaming video file (58 min.) : color, sound)Other title: SMAD phosphorylation and the TGF-β pathwaySubject(s): Cancer -- Molecular aspects | Cellular signal transduction | Phosphorylation | Proteins -- Metabolism | Transforming growth factors-beta | Cell Transformation, Neoplastic | Embryonic Development | Homeostasis | Neoplasms -- metabolism | Phosphorylation | Protein Serine-Threonine Kinases | Receptors, Transforming Growth Factor beta | Signal Transduction -- physiology | Smad Proteins -- metabolism | Transforming Growth Factor betaOnline resources: Click here to access online | Series (Molecular basis of cancer) | Series (Protein phosphorylation)
Contents:
Contents: The TGFb family as a paradigm of multifunctional cytokines -- TGFb controlling embryo development and tissue homeostasis -- TGFb receptor serine/threonine kinases -- SMADs as central TGFb signal transducers and transcriptional mediators -- Logic and organization of TGFb signaling processes -- TGFb pathway regulation and integration in the cell -- TGFb pathway disruption in heritable disorders and cancer.
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Animated audio-visual presentation with synchronized narration.

Title from title frames.

Contents: The TGFb family as a paradigm of multifunctional cytokines -- TGFb controlling embryo development and tissue homeostasis -- TGFb receptor serine/threonine kinases -- SMADs as central TGFb signal transducers and transcriptional mediators -- Logic and organization of TGFb signaling processes -- TGFb pathway regulation and integration in the cell -- TGFb pathway disruption in heritable disorders and cancer.

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