Chemical synthesis of peptides and peptide libraries [electronic resource] / Victor J. Hruby.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Chemical biology : the role of chemistry in our fundamental understanding of biology: Publisher: London : Henry Stewart Talks, 2022Description: 1 online resource (1 streaming video file (41 min.) : color, sound)Subject(s): Amino acid sequence | Peptides | Drug Design | Peptide Library | Peptides -- chemistryOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Updated version of a talk first published in 2008
Contents: Peptide and protein synthesis is the most robust of all synthetic chemistries -- Very large combinatorial libraries with billions of different peptides are possible -- Highly constrained peptides with specific secondary (phi/psi space) and tertiary (chi space) structures can be designed and synthesized -- Peptides stable to proteolytic degradation and able to cross BBB can be synthesized -- Peptides designed and synthesized with potent and selective bioactivities -- Many excellent drugs -- Peptide synthesis a critical tool for all aspects of chemical biology.
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Mode of access: World Wide Web.