Hormonal influence on bone remodeling and its implications for the pathophysiology of osteoporosis [electronic resource] / Stavros Manolagas.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. World of hormones : molecular and physiological insights: Publisher: London : Henry Stewart Talks, 2020Description: 1 online resource (1 streaming video file (51 min.) : color, sound)Subject(s): Bone remodeling | Bones -- Physiology | Osteoporosis -- Endocrine aspects | Osteoporosis -- Hormone therapy | Osteoporosis -- Pathophysiology | Age Factors | Bone and Bones -- metabolism | Bone Diseases, Metabolic | Bone Remodeling | Estrogens | Glucocorticoids -- adverse effects | Hormones | Minerals -- metabolism | Osteoclasts | Osteocytes | Osteoporosis -- physiopathology | Osteoporosis -- therapy | Oxidative StressOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Updated version of a talk first published in 2007.
Contents: Birth and fate of osteoblasts and osteoclasts -- Mechanical loading -- Role of osteocytes in mineralization -- Sclerostin -- The cell number concept -- Osteoporosis -- Anti-osteoporotic effects of sex steroids and their cellular mechanisms -- Transcriptional regulation by estrogens -- Glucocorticoid-induced bone disease -- Glucocorticoids induce osteocyte apoptosis -- Effects of thyroid hormones on the skeleton -- Involutional osteoporosis -- Age-dependent skeletal deterioration -- Age-associated oxidative stress -- Future implications.
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Mode of access: World Wide Web.