Protein oxidation and removal of oxidized proteins by proteolysis [electronic resource] / Tilman Grune.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Free radicals and the oxygen paradox : oxidative stress in biology, aging and disease: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (39 min.) : color, sound)Subject(s): Free Radicals | Oxidative StressOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Oxidized proteins -- Intracellular proteases -- The 20S core proteasome -- Proteasomal particles -- The proteasome-ubiquitin system -- Protein oxidation and proteasome -- Degradation of oxidized proteins and protein function -- Protein surface hydrophobicity -- Unfolding of oxidized proteins -- Stability of the 20S proteasome towards oxidation -- Oxidative stress and protein turnover -- Oxidation-induced proteolysis -- Degradation of oxidized proteins in cells -- What happens if degradation fails? -- Protein aggregates inhibit the proteasome -- Particle uptake by fibroblasts
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Mode of access: World Wide Web.