Colorectal cancer and hereditary colon cancer syndromes [electronic resource] / Carol A. Burke.

By: Burke, Carol A [spk]Material type: FilmFilmSeries: Henry Stewart talksBiomedical & life sciences collection. Gastroenterology and hepatology: Publisher: London : Henry Stewart Talks, 2011Description: 1 online resource (1 streaming video file (45 min.) : color, sound)Subject(s): Colorectal Neoplasms | Gastroenterology | Neoplastic Syndromes, HereditaryOnline resources: Click here to access online | Series
Contents:
Contents: Colorectal cancer is a molecularly heterogeneous disease known to arise from two distinct origins, the adenomatous and serrated pathways -- Sessile serrated polyps, also known as sessile serrated adenomas, and traditional serrated adenomas are believed to be the precursor lesions for serrated carcinomas which account for up to 30% of sporadic colorectal cancers -- When colorectal polyps or cancer occur in multiple generations, numerous relatives, at a young age of onset or in association with unusual numbers of lesions or extra-colonic tumors, a hereditary colorectal cancer syndrome should be suspected as a potential cause -- The ability to recognize a patient with a hereditary colorectal cancer syndrome allows a practitioner to stratify her or his patient's lifetime cancer risk and devise prevention and management strategies for risk reduction in the patient and family once the diagnosis is confirmed.
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Contents: Colorectal cancer is a molecularly heterogeneous disease known to arise from two distinct origins, the adenomatous and serrated pathways -- Sessile serrated polyps, also known as sessile serrated adenomas, and traditional serrated adenomas are believed to be the precursor lesions for serrated carcinomas which account for up to 30% of sporadic colorectal cancers -- When colorectal polyps or cancer occur in multiple generations, numerous relatives, at a young age of onset or in association with unusual numbers of lesions or extra-colonic tumors, a hereditary colorectal cancer syndrome should be suspected as a potential cause -- The ability to recognize a patient with a hereditary colorectal cancer syndrome allows a practitioner to stratify her or his patient's lifetime cancer risk and devise prevention and management strategies for risk reduction in the patient and family once the diagnosis is confirmed.

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