Winner's curse, replication and meta-analysis [electronic resource] / Frank Dudbridge.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Statistical genetics: Publisher: London : Henry Stewart Talks, 2016Description: 1 online resource (1 streaming video file (38 min.) : color, sound)Subject(s): Gene mapping -- Statistical methods | Genetics -- Statistical methods | Biometry | Chromosome Mapping -- methods | Computational Biology -- methods | Data Interpretation, Statistical | Genetics -- statistics & numerical data | Genome-Wide Association Study -- methods | Models, Statistical | Statistics as TopicOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Winner's curse: tendency to see a larger effect than usual upon discovery -- Examples from GWAS -- Methods for obtaining unbiased estimates -- Replication: confirming genetic associations in further studies -- Technical, direct and indirect replication -- Meta-analysis: combining multiple GWAS -- Forest plots, fixed and random effects, sources of heterogeneity in GWAS.
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Mode of access: World Wide Web.