Genetic determinants of metabolism [electronic resource] : clinical applications in psychiatry / Julia Kirchheiner [Stingl].
Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Psychopharmacogenetics : genetic factors influencing the kinetics and dynamics of psychotropic drugs: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (36 min.) : color, sound)Subject(s): Mental Disorders -- drug therapy | Metabolism -- genetics | Pharmacogenetics | Psychopharmacology | Psychotropic DrugsOnline resources: Click here to access online | SeriesAnimated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Factors that determine psychiatric importance of genetic variants -- Consequences which arise from genotyping -- Drugs are metabolized via the polymorphic cytochrome P450 enzyme CYP2D6 -- Differences in pharmacokinetic parameters for tricyclics, some SSRIs, other antidepressants, typical and some atypical antipsychotic drugs -- Effects on therapeutic efficacy and adverse events -- Indication for genotyping in psychotropic drug treatment -- Future research to close the gap between pharmacogenetic research and clinical practice.
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Mode of access: World Wide Web.