Autophagy dysfunction in lysosomal storage disorders [electronic resource] / Carmine Settembre.
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FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Autophagy and lysosomal storage diseases: Publisher: London : Henry Stewart Talks, 2019Description: 1 online resource (1 streaming video file (24 min.) : color, sound)Subject(s): Cell death | Lysosomal storage disorders | Lysosomes | Autophagy -- drug effects | Autophagy -- physiology | Lysosomal Storage Diseases | Lysosomes -- metabolism | Mechanistic Target of Rapamycin Complex 1Online resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Overview of the lysosome and autophagy -- Lysosomal storage disorders (LSDs) -- Lysosomal vacuolization -- Accumulation of LC3+ vesicles -- Studying co-localization of Lamp1 with LC3 and p62 -- LC3-tandem assay to study AV-lysosome fusion -- mTORC1 inhibitors and AV-lysosome fusion -- Pharmacological modulation of autophagy.
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Mode of access: World Wide Web.