Novel lipid mediators in resolution of inflammation [electronic resource] / Charles N. Serhan.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Innate immunity : host recognition and response in health and disease: Publisher: London : Henry Stewart Talks, 2009Description: 1 online resource (1 streaming video file (38 min.) : color, sound)Subject(s): Immunity, Innate | Inflammation | LipidsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Complete resolution of the acute inflammatory response and its return to homeostasis is essential -- Efforts to identify and characterize the cellular and molecular mechanisms that govern resolution of self-limited inflammation -- Systems approach with temporal analysis of the evolving inflammatory exudates using unbiased mediator lipidomics/informatics, proteomics, and cellular traffic with murine resolving exudates -- Novel endogenous pathways of local acting mediators that are dual acting, and that are both anti-inflammatory and pro-resolving -- Biosynthesis and actions of "resolvins" and "protectins" -- E-series resolvins and D-series resolvins -- Actions of neuroprotectin D-1 -- Biosynthesis of aspirin-triggered lipid mediators and their impact in regulating acute inflammatory responses -- The resolution of acute inflammation is an active process that can be accelerated.
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Mode of access: World Wide Web.